Life development is a dynamic process in which multiple cell types interact with each other in a three-dimensional space. Therefore, spatial analysis of cell types and their interactions is the basis of developmental research. Spatial transcriptome technology -- Stereo-seq, can map the complex interactions of various cell types during developmental stages at the molecular level, profoundly advancing the field of development with unprecedented precision and complexity. For example, a 3D spatiotemporal atlas of the entire developmental cycle of Drosophila provides a unique data reference on the spatial structural basis of the emergence of various cell types during Drosophila development, their interactions with other cell types, and other related relevant molecular events.