STOmics STOmics

The only spatial technology empowers you with both
unprecedented field of view and unbiased transcriptome
captured in nanoscale resolution
STOmics> Why Stereo-seq
Technical Principles Technical highlights Research Areas What customers are saying
Technical Principles

STOmics proprietary Stereo-seq (SpaTial Enhanced REsolution Omics-sequencing) technology offers researchers a novel tool to explore spatial biology with unprecedented field-of-view, and subcellular resolution, enabling simultaneous transcriptome study and analysis at tissue-, cellular-, subcellular- and molecular level from fresh frozen tissue. Stereo-seq captures mRNA within the tissue on the chip and restores cellular spatial location through spatial coordination barcoding (Coordinate ID, CID), realizing in situ sequencing of tissues for establishing a strong research foundation for in-depth understanding of the relationship among gene expression, cell morphology and cellular microenvironments.

Technical highlights
Integration of pathology and spatio-temporal omics

Our innovative staining approach made it possible to integrate the study of pathology and spatio-temporal analysis on the same tissue section.

Large field of view and high resolution

With up to decimeter-scale STOmics Chip and nanoscale DNB probes, subcellular level details can be collected from any position on an entire tissue section.

Multidimensional analysis

Made it possible to integrate the study of tissue staining sections with whole-genome mRNA transcriptomics and proteomics.

High compatibility

Stereo-seq is compatible with fresh frozen samples, and has reliable performance on cells, organs, and embryo sections of various animal and plant species.

Research Areas

Through massive implementation in life Spatio-temporal atlas, species evolution, disease diagnosis, therapy, and prognosis, Stereo-seq and its future technical variations will thus be highly transformative for multiple research fields. It will enhance the overall understanding of human life and advance the redefinition of diseases.

What customers are saying
“When I first saw the data, my reaction was ‘Extraordinary’! Because it was the first time we were able to see the single-cell resolution in spatial context… BGI’s STOmics technology allows us not only to identify different cell types in a tumor, but also allows us to understand where they are sitting, with whom they are talking, and what they are talking.”
Dr. Ankur Sharma, Head of Onco-Fetal Ecosystem Laboratory at the Harry Perkins Institute of Medical Research
Stereo sequencing is a method that allows us to map the cells in the tissue. With that technique, we can identify every single cell and position these cells in the tissue. This was not possible in the past. It really opens up new possibilities to understand cell-cell communication.
Dr. Christ Marine, Science Director, VIB - KU Leuven Center for Cancer Biology Full Professor, Dept. of Oncology, KU Leuven, Belgium