Cell heterogeneity and its spatial structure play an important role in disease development and treatment. For example, tumor cell heterogeneity and microenvironment are key to research on tumor mechanism, prevention, and treatment. Spatial transcriptome technology -- Stereo-seq, can map tumor cell heterogeneity and microenvironment structure at the molecular level, bringing significant breakthroughs in tumor research. Similarly, spatial transcriptome technology can also be applied to other diseases that are tied to spatial structures, providing a powerful tool for further exploration.